Activity of WG4
2nd Training School on PET radionuclide generators
2nd Training School on PET-radionuclide generators for trivalent metals: 68Ge/68Ga and 44Ti/44Sc will be held on September 14 – 16, 2010 at the Institute of Nuclear Chemistry, Fritz-Strassmann-Weg 2 Johannes Gutenberg-University Mainz Germany. For more info download the flyer
Download Training school 2010 flyer.pdfWG4 - Radionuclides
Alpha-, Auger- and/or beta-electron emitting radionuclides in therapeutic applications as well as gamma and positron emitters in diagnostic applications are of interest of the projects carried out by WG4. Radionuclides of interest, their availability as well as problems related to their practical use for labeling of various biomolecules such as specific activity, competing metals etc, are being investigated. WG4 Radionuclides develops projects related to: Radionuclide production (new targets, new radionuclides), possibilities for production of high specific activity therapeutic radionuclides in nuclear reactors and in cyclotrons, development of technologies for production of isotopes suitable in the process of treatment planning, follow up and for therapy Radionuclide generator design (implementation of innovative separation techniques such as membrane separation, electrochemical methods, new adsorbents, composites, polymers etc. ) and development of methods aimed at efficient use of existing generator types Development of ligands for well established and "exotic" radioisotopes Exchange of information between the groups on the separation techniques involved into the isotope manufacturing process, implementation of these techniques to develop generator-like techniques Providing information to other WGs on isotopes availability, practical aspects of their use, radionuclidic impurities, decay products, chemical impurities and other parameters which may influence their performance in animals and in humans Support for safe handling of these radioisotopes, developments in analytical techniques used for evaluation of these isotopes and radiolabelled ligands Bridging PECT/CT imaging with radiotherapy by using identical targeting vectors, but different adequate radionuclides Development of Good Radiopharmacy Practice procedures and recommendations Legal aspects of handling and use of radionuclides and generators Characterization of offered radionuclides as potential precursors for labelling for radiopharmaceuticals used in clinical trials (as investigational medicinal products) Bringing in information on the developments resulting from other research programs, as example - International Atomic Energy Agency coordinated research programs

